CannOmega –Endocannabinoid System Support

           THE SYSTEM:

The endocannabinoid system is present in all living creatures and serves to regulate cellular homeostasis. Cannabinoid receptors are present on every cell of the body and are stimulated by endogeneous cannabinoids. CBD is a phytocannabinoid that stimulate these receptors directly as well as indirectly by regulating enzymes that produce endogenous cannabinoids.

Omega fatty acids are considered essential in that they cannot be produced by the body and must be ingested. They are a structural component of all cell membranes and are important in the maintenance and formation of endocannabinoid receptors. Omega 3 and 6 fatty acids are precursors in the formation of the transmitters that regulate the endocannabinoid receptors.

THE PROBLEM:

 A proper balance of omega 3 and omega 6 essential fatty acids is necessary for the formation and maintenance of a functional endocannabinoid system that will maintain cellular balance. Omega 6 fatty acids (overabundant in normal diets) are precursors to inflammatory mediators and “bad” endocannabinoids, which can lead to overstimulation resulting in down regulation of the endocannabinoid system.  Omega 3 fatty acids (deficient in normal diets) are precursors to anti-inflammatory mediators and become “good” endocannabinoids that counteract this overstimulation and down regulation.

Clinical Endocannabinoid Deficiency Syndrome (CEDS) results from the lack of “good” endogenous cannabinoids, which is caused by an omega 3 deficiency, resulting in an imbalanced endocannabinoid system.  In other words, the system that is designed to balance cellular function, needs itself to be balanced by maintaining a proper omega 3:6 ratio. By supplementing with phytocannabinoids and omega 3 fatty acids together, CEDS can be treated more effectively than with phytocannabinoids alone.

Administration of CBD under the tongue (sublingual) provides the best absorption directly into the blood stream.  This is difficult to do in animals and it is easiest to administer on food.  This results in small intestinal absorption and first pass metabolism in the liver, which removes 80% of the ingested dose before it reaches the blood stream.

Studies show that a combining CBD with long chain fatty acids (omega 3 fatty acids) results in the encapsulation of CBD within the fats resulting in micelles, which are absorbed by the lymphatic system and enter the blood stream, bypassing the first pass liver metabolism.  This results in a 2.5-3 fold increase in blood levels over CBD ingestion without fatty acids.

Not all omega 3 supplements are the same.  Most fish oil supplements are concentrated into an ester form, allowing for double and triple strength levels of omega 3 fatty acids.  Although they are more concentrated, they are much less bioavailable and are much more highly oxidized, depleting the body’s antioxidant stores.  The triglyceride form of fish oil is the natural state of omega 3 fatty acids allowing for optimal absorption and when processed correctly, minimal oxidation.

THE SOLUTION:

CannOmega has been developed by Veterinarians who have provided care for their patients for almost 4 decades and have studied and witnessed the benefits of omega 3 supplementation for numerous health issues.  Our understanding of the endocannabinoid system and its dependence on omega fatty acids for it’s very existence led us to a unique combination that has unmatched absorption and provides necessary balancing of this vitally important homeostatic system.

We grow our hemp in Western Colorado and have control of the genetics of seed production, planting and cultivation, irrigation, harvest and extraction of oils used in CannOmega.   These oils are full spectrum phytocannabinoids (not CBD isolates), which take advantage of the “entourage effect” of the over 100 compounds nature has provided us in the hemp plant which has served to heal mankind over centuries.

Our fish oil is of the highest quality available and is naturally of the triglyceride form for optimal absorption.  Low oxidation values mean less fishy smell, better palatability, and less oxidative stress for our pets. 

The reason some patients do not respond to CBD supplementation alone is obvious once you understand the importance of providing omega 3 to balance out the overabundance of omega 6 in most diets.  Once we repair a sick endocannabinoid system with omega 3 supplementation, then we can reap the benefits that phytocannabinoids have to offer our pets.  Thank you for caring enough about your animal companions to give them the benefits of CannOmega.

CannOmega Dosage:

Mobility/Severe osteoarthritis/Seizure disorders

     Give 1ml per 10lbs body weight twice a day

            Provides 1mg CBD/lb and 600mg EPA+DHA/lb per day

Maintenance

     Give .5ml per 10 lbs body weight once a day

            Provides .5mg CBD/lb and 300mg EPA+DHA/lb per day